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It is a CD19-directed genetically modified autologous T cell immunotherapy. Axicabtagene ciloleucel (Yescarta) is FDA approved for the treatment of adult patients with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy, including diffuse large B-cell lymphoma (DLBCL) not otherwise specified, primary mediastinal large B-cell lymphoma, high-grade B-cell lymphoma, and DLBCL arising from follicular lymphoma.Yescarta is not indicated for the treatment of patients with primary central nervous system lymphoma.

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It is made up of billions of cells that are divided into several different types. You can use the shiny new "Submit Corrections" form found on our movie and performer pages.Your submission goes into a queue and our team of editors takes it from there.The more information about the movie you can provide the better, as the longer it takes us to research a title, the longer it might take to get the movie listed.This is an increasingly common question with a difficult answer.CAR T cells that have been returned to the patient’s bloodstream multiply in number.

These are the “attacker” cells that will recognize, and attack, cells that have the targeted antigen on their surface. CAR T cells may eradicate all of the cancer cells and may remain in the body months after the infusion has been completed.

When you and your doctor discuss CAR T-cell therapy as a potential treatment option for you, it may be helpful to have In addition to speaking with your doctor, LLS Information Specialists, available at (800) 955-4572, offer guidance on how patients can work with their doctors to determine if a specific clinical trial is an appropriate treatment option.

LLS offers highly personalized clinical-trial search services, which can be accessed through our Information Specialists.

Talk with your doctor about whether participation in a CAR T-cell therapy clinical trial is an option for you.

Obtaining another opinion from a hematologist-oncologist (a blood cancer specialist), may be helpful in finding additional clinical-trial information as well.

If we have a missing movie, find one of the performers in the movie, and submit a correction with the info on the missing movie.